Jeffrey H Withey Selected Research

Cholera Toxin

1/2021	H-NS and ToxT Inversely Control Cholera Toxin Production by Binding to Overlapping DNA Sequences.
5/2015	Mechanism for inhibition of Vibrio cholerae ToxT activity by the unsaturated fatty acid components of bile.
11/2014	Bicarbonate increases binding affinity of Vibrio cholerae ToxT to virulence gene promoters.
10/2012	Identification and characterization of the functional toxboxes in the Vibrio cholerae cholera toxin promoter.
9/2009	Bicarbonate Induces Vibrio cholerae virulence gene expression by enhancing ToxT activity.
3/2006	The toxbox: specific DNA sequence requirements for activation of Vibrio cholerae virulence genes by ToxT.
12/2005	Vibrio cholerae ToxT independently activates the divergently transcribed aldA and tagA genes.

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Jeffrey H Withey Research Topics

Disease

12	Infections 07/2022 - 03/2006
6	Cholera 01/2021 - 12/2005
5	Diarrhea 01/2021 - 10/2012
1	Communicable Diseases (Infectious Diseases) 01/2022
1	Shock 01/2019

Drug/Important Bio-Agent (IBA)

7	Cholera ToxinIBA 01/2021 - 12/2005
5	Virulence Factors (Pathogenicity Factors)IBA 05/2015 - 12/2005
3	MucinsIBA 01/2021 - 08/2017
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 09/2009
2	Leukocyte L1 Antigen Complex (Calgranulin)IBA 07/2022 - 01/2022
2	16S Ribosomal RNAIBA 01/2021 - 01/2021
1	InterferonsIBA 07/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2022
1	17-hydroxyestrane-3-carbonitrile (ECN)IBA 07/2022
1	Interleukin-8 (Interleukin 8)IBA 01/2022
1	Interleukin-13IBA 01/2021
1	AntibodiesIBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	CytokinesIBA 01/2021
1	ORALIT (ORS)IBA 12/2018
1	SolutionsIBA 12/2018
1	Glucose (Dextrose)FDA LinkGeneric 12/2018
1	4-O-carboxymethylascochlorinIBA 08/2017
1	VaccinesIBA 01/2016
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2015
1	A-Form DNA (A-DNA)IBA 05/2015
1	Carrier Proteins (Binding Protein)IBA 05/2015
1	tetracarboxyphenylporphineIBA 09/2011
1	Bicarbonates (Hydrogen Carbonate)IBA 09/2009

Therapy/Procedure

2	Fluid Therapy (Oral Rehydration Therapy) 12/2018 - 12/2015
2	Therapeutics 12/2015 - 05/2015